Turkish Archives of Pediatrics
Original Article

Comparison of 2% Chlorhexidine Gluconate in 70% Alcohol and 10% Povidone-Iodine Used for Port Catheter Dressing Changes in Pediatric Hematology–Oncology Patients: A Prospective Observational Study

1.

Department of Pediatric Nursing, Hacettepe University Faculty of Nursing, Ankara, Turkey

2.

Department of Nursing, Ankara University, Ankara, Turkey

3.

Department of Pediatric Infectious Disease, Ankara City Hospital , Ankara, Turkey

4.

Department of Pediatric Hematology and Oncology, Gulhane Training and Research Hospital, Ankara, Turkey

Turk Arch Pediatr 2021; 56: 451-457
DOI: 10.5152/TurkArchPediatr.2021.21035
Read: 87 Downloads: 38 Published: 01 September 2021

Objective: This study aimed to compare the effectiveness of 2% chlorhexidine gluconate in 70% alcohol with that of 10% povidone-iodine, for dressing changes in pediatric hematology–oncology patients with port catheters, in preventing catheter-related bloodstream infection (CRBSI).

Methods: In this prospective, multicenter, observational, and cross-sectional study, 45 patients (25 patients for chlorhexidine, 20 patients for povidone-iodine) with port catheters were evaluated from January 2018 to May 2019. The sociodemographic, clinical, and port catheter-related variables were evaluated. The mean age of the patients was 6.28 ± 4.58 years, and 60% of patients were female.

Results: Among the patients whose dressings were changed using 2% chlorhexidine gluconate in 70% alcohol, the mean number of dressing changes was 39.52 ± 29.7 and the rates of exit-site infection and CRBSI were 20% (2.37/1000 catheter-days) and 16% (1.90/1000 catheter-days), respectively. Among the patients whose dressings were changed using 10% povidone-iodine, the mean number of dressing changes was 48.0 ± 31.48 and the rates of exit-site infection and CRBSI were 15% (1.59/1000 catheter-days) and 10% (1.06/1000 catheter-days), respectively. None of the patients developed pocket infections. The rates of CRBSI and exit-site infections were not different between the 2 antiseptic solutions.

Conclusion: This study found no differences between the effectiveness of 2% chlorhexidine in 70% alcohol and that of 10% povidone-iodine solution in preventing CRBSI. Therefore, both solutions can be used in dressing changes.

Cite this article as: Bakır E, Sezer TA, Çavuşoğlu H, Özkaya Parlakay A, Gürsel O. Comparison of 2% chlorhexidine gluconate in 70% alcohol and 10% povidone-iodine used for port catheter dressing changes in pediatric hematology–oncology patients: a prospective observational study. Turk Arch Pediatr. 2021; 56(5): 451-457.

Files
EISSN 2757-6256