Turkish Archives of Pediatrics
Original Article

Comparison of 2% Chlorhexidine Gluconate in 70% Alcohol and 10% Povidone-Iodine Used for Port Catheter Dressing Changes in Pediatric Hematology–Oncology Patients: A Prospective Observational Study


Department of Pediatric Nursing, Hacettepe University Faculty of Nursing, Ankara, Turkey


Department of Nursing, Ankara University, Ankara, Turkey


Department of Pediatric Infectious Disease, Ankara City Hospital , Ankara, Turkey


Department of Pediatric Hematology and Oncology, Gulhane Training and Research Hospital, Ankara, Turkey

Turk Arch Pediatr 2021; 56: 451-457
DOI: 10.5152/TurkArchPediatr.2021.21035
Read: 87 Downloads: 38 Published: 01 September 2021

Objective: This study aimed to compare the effectiveness of 2% chlorhexidine gluconate in 70% alcohol with that of 10% povidone-iodine, for dressing changes in pediatric hematology–oncology patients with port catheters, in preventing catheter-related bloodstream infection (CRBSI).

Methods: In this prospective, multicenter, observational, and cross-sectional study, 45 patients (25 patients for chlorhexidine, 20 patients for povidone-iodine) with port catheters were evaluated from January 2018 to May 2019. The sociodemographic, clinical, and port catheter-related variables were evaluated. The mean age of the patients was 6.28 ± 4.58 years, and 60% of patients were female.

Results: Among the patients whose dressings were changed using 2% chlorhexidine gluconate in 70% alcohol, the mean number of dressing changes was 39.52 ± 29.7 and the rates of exit-site infection and CRBSI were 20% (2.37/1000 catheter-days) and 16% (1.90/1000 catheter-days), respectively. Among the patients whose dressings were changed using 10% povidone-iodine, the mean number of dressing changes was 48.0 ± 31.48 and the rates of exit-site infection and CRBSI were 15% (1.59/1000 catheter-days) and 10% (1.06/1000 catheter-days), respectively. None of the patients developed pocket infections. The rates of CRBSI and exit-site infections were not different between the 2 antiseptic solutions.

Conclusion: This study found no differences between the effectiveness of 2% chlorhexidine in 70% alcohol and that of 10% povidone-iodine solution in preventing CRBSI. Therefore, both solutions can be used in dressing changes.

Cite this article as: Bakır E, Sezer TA, Çavuşoğlu H, Özkaya Parlakay A, Gürsel O. Comparison of 2% chlorhexidine gluconate in 70% alcohol and 10% povidone-iodine used for port catheter dressing changes in pediatric hematology–oncology patients: a prospective observational study. Turk Arch Pediatr. 2021; 56(5): 451-457.

EISSN 2757-6256