Turkish Archives of Pediatrics
Original Article

Is there myocardial involvement in children with long-term follow-up for Kawasaki disease? A study based on two-dimensional speckle tracking echocardiography

1.

Department of Pediatric Cardiology, Kocaeli University Faculty of Medicine Kocaeli, Turkey

2.

Department of Pediatric Cardiology, Zeynep Kamil Women’s and Children’s Disease Training and Research Hospital, İstanbul, Turkey

3.

Department of Pediatric Cardiology, Trakya University School of Medicine Edirne, Turkey

Turk Arch Pediatr 2021; 56: 44-50
DOI: 10.5152/TurkArchPediatr.2020.20193
Read: 54 Downloads: 26 Published: 30 December 2020

Objective: This study aimed to determine the possibility of subclinical myocardial dysfunction detected by strain echocardiography in the late period of children with Kawasaki disease.

Material and Methods: The study enrolled 30 patients with Kawasaki disease with a follow-up period of at least 12 months and 30 healthy age- and gender-matched children. During the follow-up period, standard echocardiography, pulsed and tissue Doppler, and strain echocardiography were recorded for both groups.

Results: The mean age at the time of the diagnosis was 2.6±2.3 years (2 months–11 years). The mean follow-up period after the diagnosis was 3.55±2.20 years. Conventional echocardiography, M mode, pulsed and tissue Doppler values, and myocard performance index did not reveal significant differences. Left ventricle strain and strain rate parameters obtained by apical four-, three-, and two-chamber views did not show statistical differences between patients and controls. There was a positive correlation between the duration of follow-up and global four- and three-chamber longitudinal strain and global longitudinal strain values (r=0.465, p=0.010; r=0.414, p=0.023; r=0.492, p=0.006, respectively), whereas global radial strain showed negative correlation (r=−0.517, p=0.003).

Conclusion: The analysis of systolic strain and strain rate did not detect a subclinical myocardial dysfunction in the long-term follow-up of Kawasaki disease. However, strain values showed variability with the follow-up periods, which indicates that Kawasaki disease might cause left ventricular dysfunction in the later phases. Therefore, a follow-up of children with a diagnosis of Kawasaki disease is of capital importance.

Cite this article as: Kayabey Ö, Tuncer T, Deveci M, Başar EZ, Babaoğlu K. Is there myocardial involvement in children with long-term follow-up for Kawasaki disease? A study based on two-dimensional speckle tracking echocardiography. Turk Arch Pediatr 2021; 56(1): 44-50.

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